Welcome to the Homepage for Ehrlichial Research Laboratory at the Ohio State University, College of Veterinary Medicine, Department of Veterinary Biosciences.

    The objectives of ehrlichial research in our laboratory are to understand the molecular pathogenesis of ehrlichiosis, including signal transduction pathways for survival of ehrlichiae in leukocytes, differential gene expression; to elucidate the cycle of transmission and maintenance of Ehrlichia spp., Anaplasma spp., Neorickettsia spp.; and to compare three major human ehrlichiosis agent genome sequences.

• Our lab has moved to Veterinary Medicine Acedemic Building (VMAB Room 425 and 431).
• Classification and Nomenclature changes for Ehrlichia and related species (please read "Background section" and phylogram based on 16S rRNA for more information):
  • The Tribe Ehrlichieae and the genus Wolbachia are indeed in the Family Anaplasmataceae.
  • HGE agent, Ehrlichia equi, and E. phagocytophila become Anaplasma phagocytophilum.
  • Ehrlichia platys becomes Anaplasma platys.
  • Ehrlichia senetsu and E. risticii become Neorickettsia sennetsu and N. risticii respectively.
  • Cowdria ruminantium becomes Ehrlichia ruminantium.
  • Haemobartonella and Eperythrozoon sp. becomes Mycoplasma spp.