Selected Publications in Referred Journals:      Back to Publications Page   

1. Lin, M., C. Zhang, K. Gibson, and Y. Rikihisa. (2009) Analysis of Complete Genome Sequence of Neorickettsia risticii: Causative Agent of Potomac Horse Fever. Nucleic Acids Res. 37(18): 6076-6091. [Link to Pubmed]
2. Xiong, Q., M. Lin, and Y. Rikihisa. (2009) Anaplasma phagocytophilum acquires cholesterol through low-density lipoprotein uptake pathway. PLoS Pathog. 5: e1000329. [PMCID: PMC2654415] | [Link to Pubmed]
3. Bao, W.†, Y. Kumagai†, H. Niu, Y. Yamaguchi, K. Miura, and Y. Rikihisa. (†equally contributed) (2009) Four VirB6 paralogs and VirB9 are expressed and interact in Ehrlichia chaffeensis-containing vacuoles. J. Bacteriol. 191: 278-286. [PMCID: PMC2612412] | [Link to Pubmed]
4. Lai, T.H., Y. Kumagai, M. Hyodo, Y. Hayakawa, and Y. Rikihisa. (2009) The Anaplasma phagocytophilum PleC histidine kinase and PleD diguanylate cyclase two-component system and role of cyclic Di-GMP in host cell infection. [Comment in: J Bacteriol. 2009 Feb;191(3):683-6] J. Bacteriol. 191: 693-700. [PMCID: PMC2632110] | [Link to Pubmed]
5. Rikihisa, Y., M. Lin, H. Niu, and Z. Cheng. (2009) Type IV Secretion System of Anaplasma phagocytophilum and Ehrlichia chaffeensis. In: Rickettsiology and Rickettsial Diseases-Fifth International Conference. Edited by Karim E. Hechemy; Philippe Brouqui; James E. Samuel; and Didier A. Raoult. Ann. N. Y. Acad. Sci. 1166: 106-111. [Link to Pubmed]
6. Miura, K., and Y. Rikihisa. (2009) Liver microarray profiles associated with strain-specific Ehrlichia chaffeensis–induced hepatitis in mice. Infect. Immun. 77: 245-254.  [Link to Pubmed]
7. Grieg, J., Y. Rikihisa, and M. Wellman. (2009) Importance of the use of PCR in confirmation of Ehrlichia ewingii infection. Vet. Clin. Pathol. In Press.  [Link to Pubmed]
8. Mottaz-Brewer, Heather M., A. D. Norbeck, J. N. Adkins, N. P. Manes, C. K. Ansong, L. Shi, Y. Rikihisa, T. Kikuchi, S. W. Wong, R. D. Estep, F. Heffron, L. Pasa-Tolic, and R. D. Smith. (2008) Optimization of proteomic sample preparation procedures for comprehensive protein characterization of pathogenic systems. J. Biomol. Tech. 19: 285-295. [PMCID: PMC2628077] | [Link to Pubmed]
9. Schaefer, J. J., J. Kahn, G. R. Needham, Y. Rikihisa, S. A. Ewing and R. W. Stich. (2008) Antibiotic Clearance of Ehrlichia canis from Dogs Infected by Intravenous Inoculation of Carrier Blood. Ann. N.Y. Acad. Sci. (Animal Biodiversity and Emerging Diseases) 1149: 263-269. [Link to Pubmed]
10. Delos Santos, J. R., M. Oglesbee M, Y. Rikihisa., R. W. Stich (2008) Pathologic Evidence of Ehrlichiosis in Calves Inoculated with Ehrlichia chaffeensis. Ann. N.Y. Acad. Sci. (Animal Biodiversity and Emerging Diseases) 1149: 103-106. [Link to Pubmed]
11. Unver, A., Y. Rikihisa, M. Karaman, and H. Ozen. (2008) An acute severe ehrlichiosis in a dog experimentally infected with a new virulent strain of Ehrlichia canis. Clin. Microbiol. Infect. Dis. 15 (Suppl. 1): 1-3.  [Link to Pubmed]
12. Huang, H. †, M. Lin †, X. Wang, T. Kikuchi, H. Mottaz, A. Norbeck, and Y. Rikihisa. († Equally Contributed) (2008) Proteomic Analysis of and Immune Responses to Ehrlichia chaffeensis Lipoproteins. Infect. Immun. 76: 3405-3414. [PMCID: PMC2493228] | [Link to Pubmed]
13. Kumagai, Y., H. Huang, and Y. Rikihisa. (2008) Expression and Porin Activity of P28 and OMP-1F during intracellular Ehrlichia chaffeensis Development. J. Bacteriol. 190: 3597-3605. [PMCID: PMC2394992] | [Link to Pubmed]
14. Gibson, K.E. and Y. Rikihisa. (2008) Molecular link of different stages of the trematode host of Neorickettsia risticii to Acanthatrium oregonense. Environ. Microbiol. 10: 2064-2073. [Link to Pubmed]
15. Zhang, C., Q. Xiong, T. Kikuchi, and Y. Rikihisa. (2008) Identification of 19 polymorphic major outer membrane protein genes and their immunogenic peptides in Ehrlichia ewingii for use in a serodiagnostic assay. Clin. Vaccine Immunol. 15: 402-411. [PMCID: PMC2268259] | [Link to Pubmed]
16. Cheng, Z., X. Wang, and Y. Rikihisa. (2008) Regulation of Type IV Secretion Apparatus Genes during Ehrlichia chaffeensis Intracellular Development by a Previously Unidentified Protein. J. Bacteriol. 190: 2096-2105. [PMCID: PMC2258868] | [Link to Pubmed]
17. Xiong, Q., W. Bao, Y. Ge, and Y. Rikihisa (2008) Ehrlichia ewingii Infection Delays Spontaneous Neutrophil Apoptosis Through Stabilization of Mitochondria. J. Infect. Dis. 197: 1110-1118.  [Link to Pubmed]
18. Delos Santos, J.R., K. Boughan, W.G. Bremer, B. Rizzo B, J.J. Schaefer, Y. Rikihisa, G. R. Needham, L.A. Capitini, D. E. Anderson, M. Oglesbee, S.A. Ewing, R. W. Stich (2007) Experimental infection of dairy calves with Ehrlichia chaffeensis J. Med. Microbiol. 56: 1660-1668.  [Link to Pubmed]
19. Niu, H., M. Yamaguchi, and Y. Rikihisa (2007) Subversion of cellular autophagy by Anaplasma phagocytophilum. Cell. Microbiol. 10: 593-605.  [Link to Pubmed]
20. Ge, Y. and Y. Rikihisa. (2007) Identification of Novel Surface Proteins of Anaplasma phagocytophilum by Affinity Purification and Proteomics. J. Bacteriol. 189: 7819-7828. [PMCID: PMC2168727] | [Link to Pubmed]
21. Wang, X., Z. Cheng, C. Zhang, T. Kikuchi, and Y. Rikihisa (2007) Anaplasma phagocytophilum p44 mRNA expression is differentially regulated in mammalian and tick host cells: Involvement of the DNA binding protein ApxR. J. Bacteriol. 189: 8651-8659. [PMCID: PMC2168941] | [Link to Pubmed]
22. Schaefer, J.J., J. Kahn, G. R. Needham, Y. Rikihisa, S. A. Ewing and R. W. Stich. (2007) Antibiotic clearance of Ehrlichia canis from dogs infected by intravenous inoculation of carrier blood. Antimicrob. Agents Chemother. 51: 3394-3396. [PMCID: PMC2043173] | [Link to Pubmed]
23. Lin, M., A. den Dulk-Ras, P. JJ Hooykaas, and Y. Rikihisa (2007) Anaplasma phagocytophilum AnkA Secreted by Type IV Secretion System is Tyrosine Phosphorylated by Abl-1 to Facilitate Infection. Cell. Microbiol. 9: 2644-2657. [Link to Pubmed]
24. Ge, Y. and Y. Rikihisa. (2007) Surface-exposed proteins of Ehrlichia chaffeensis. Infect. Immun. 75: 3833-3841. [PMCID: PMC1951975] | [Link to Pubmed]
25. Miura, K. and Y. Rikihisa. (2007) Virulence potential of Ehrlichia chaffeensis strains of distinct genome sequences. Infect. Immun. 75: 3604-3613. [PMCID: PMC1932932] | [Link to Pubmed]
26. Wang, X., T. Kikuchi, and Y. Rikihisa. (2007) Proteomic Identification of A Novel Anaplasma phagocytophilum DNA Binding Protein That Regulates A Putative Transcription Factor. J. Bacteriol. 189: 4880-4886. [PMCID: PMC1913470] | [Link to Pubmed]
27. Huang, H., X. Wang, T. Kikuchi, Y. Kumagai, and Y. Rikihisa. (2007) Porin Activity of Anaplasma phagocytophilum Outer Membrane Fraction and Purified P44. J. Bacteriol. 189: 1998-2006. [PMCID: PMC1855737] | [Link to Pubmed]
28. Xiong, Q., X. Wang, and Y. Rikihisa. (2007) High-Cholesterol Diet Facilitates Anaplasma phagocytophilum Infection and Up-regulates MIP-2 and CXCR2 Expression in Apolipoprotein E-Deficient Mice. J. Infect. Dis. 195: 1497-1503. [Link to Pubmed]
29. Lin, M., and Y. Rikihisa. (2007) Degradation of p22phox and Inhibition of Superoxide Generation by Ehrlichia chaffeensis in Human Monocytes. Cell. Microbiol. 9: 861-874. [Link to Pubmed]
30. Kumagai, Y., Z. Cheng, M. Lin, and Y. Rikihisa. (2006) Biochemical Activities of Three Pairs of Ehrlichia chaffeensis Two-Component Regulatory System Involved in Inhibition of Lysosomal Fusion. Infect. Immun. 74: 5014-5022. [PMCID: PMC1594868] | [Link to Pubmed]
31. Unver, A., H. Huang, and Y. Rikihisa. (2006) Cytokine Gene Expression by Peripheral Blood Leukocytes in Dogs Experimentally Infected with a New Virulent Strain of Ehrlichia canis. Ann. N. Y. Acad. Sci. 1078: 482-486.  [Link to Pubmed]
32. Perez, M., M. Bodor, C. Zhang, Q. Xiong, and Y. Rikihisa. (2006) Human Infection with Ehrlichia canis Accompanied By Clinical Signs In Venezuela. Ann. N. Y. Acad. Sci. 1078: 110-117.  [Link to Pubmed]
33. Rikihisa, Y. (2006) New Findings on Members of the Family Anaplasmataceae of Veterinary Importance. Ann. N. Y. Acad. Sci. 1078: 438-445.  [Link to Pubmed]
34. Ge, Y. and Y. Rikihisa. (2006) Anaplasma phagocytophilum delays spontaneous human neutrophil apoptosis by modulation of multiple apoptotic pathways. Cell. Microbiol. 8: 1406-1416.  [Link to Pubmed]
35. Cheng, Z., Y. Kumagai, M. Lin, C. Zhang, and Y. Rikihisa. (2006) Intra-leukocyte expression of two-component systems in Ehrlichia chaffeensis and Anaplasma phagocytophilum and effects of the histidine kinase inhibitor closantel. Cell. Microbiol. 8: 1241-1252.  [Link to Pubmed]
36. Dunning Hotopp, J., M. Lin, R. Madupu, J. Crabtree, S. Angiuoli, J. Eisen, R. Sesahdri, Q. Ren, T. R. Utterback, S. Smith, M. Lewis, H. Khouri, C. Zhang, H. Niu, Q. Lin, N. Ohashi, N. Zhi, W. Nelson, L. M. Brinkac, R. J. Dodson, M. J. Rosovitz, J. Sundaram, S. C. Daugherty, T. Davidsen, A. Durkin, M. Gwinn, D. H. Haft, J. D. Selengut, S.A. Sullivan, N. Zafar, L. Zhou, F. Benahmed, H. Forberger, R. Halpin, S. Mulligan, J. Robinson,Y. Rikihisa, H. Tettelin. (2006) Comparative Genomics of Emerging Human Ehrlichioisis Agents. PLoS Genetics 2: e21. [PMCID: PMC1366493] | [Link to Pubmed]
37. Niu, H., Y. Rikihisa, M. Yamaguchi, and N. Ohashi (2006) Differential Expression of VirB9 and VirB6 During Lifecycle of Anaplasma phagocytophilum in Human Leukocytes is Associated with Differential Binding and Avoidance of Lysosome Pathway. Cell. Microbiol. 8: 523-534.  [Link to Pubmed]
38. Rikihisa, Y. (2006) Ehrlichia subversion of host innate immune responses. Curr. Opin. Microbiol. 9: 95-101.  [Link to Pubmed]
39. Kawahara, M, Y. Rikihisa, Q. Lin, E. Isogai, K. Tahara, A. Itagaki, Y. Hiramitsu, and T. Tajima. (2006) Genetic variants of Anaplasma phagocytophilum, Anaplasma bovis, Anaplasma centrale and Ehrlichia species in wild deer on two major islands in Japan. Appl. Environ. Microbiol. 72: 1102-1109. [PMCID: PMC1392898] | [Link to Pubmed]
40. Wang, X., T. Kikuchi, and Y. Rikihisa (2006) Two monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms. Infect. Immun. 74: 1873-1882. [PMCID: PMC1418626] | [Link to Pubmed]
41. Huang, H., A. Unver, M. J. Perez, N. G. Orellana, and Y. Rikihisa (2006) Prevalence and molecular analysis of Anaplasma platys from dogs in Lara, Venezuela. Brazilian J. Microbiol. 36: 211-216.  [Link to Pubmed]
42. Lin, Q. C. Zhang, and Y. Rikihisa (2006) Analysis of Involvement of the RecF Pathway in p44 Recombination in Anaplasma phagocytophilum and in Escherichia coli by Using a Plasmid Carrying the p44 Expression and p44 Donor Loci. Infect. Immun. 74: 2052-2062. [PMCID: PMC1418890] | [Link to Pubmed]
43. Tajima, T. and Y. Rikihisa. (2005) Cytokine Responses in Dogs Infected with Ehrlichia canis Oklahoma Strain. Ann. N. Y. Acad. Sci. 1063: 429-431.  [Link to Pubmed]
44. Lin, Q. and Y. Rikihisa. (2005) Establishment of cloned Anaplasma phagocytophilum and analysis of p44 Gene conversion within infected horse and SCID mice. Infect. Immun. 73: 5106-5114. [PMCID: PMC1201200 ] | [Link to Pubmed]
45. Bremer, W.G., J.J. Schaefer, E.R. Wagner, S.A. Ewing, Y. Rikihisa, G.R. Needham, S. Jittapalapong, D.L. Moore, and R.W. Stich. (2005) Transstadial and intrastadial experimental transmission of Ehrlichia canis by male Rhipicephalus sanguineus. Vet. Parasitol. 131: 95-105.  [Link to Pubmed]
46. Unver, A., Y. Rikihisa, K. BORKU, Y. E. OZKANLAR, and B. HANEDAN. (2005) Molecular detection and characterization of Ehrlichia canis from dogs in Turkey. Berl. Münch. Tierärztl. Wschr. 118: 300-304.  [Link to Pubmed]
47. Gibson, K.E., Y. Rikihisa, C. Zhang, and C. Martin. (2005) Neorickettsia risticii is vertically transmitted in the trematode Acanthatrium oregonense and horizontally transmitted to bats. Environ. Microbiol. 7: 203-212.  [Link to Pubmed]
48. Ge, Y., K. Yoshiie, F. Kuribayashi, M. Lin, and Y. Rikihisa. (2005) Anaplasma phagocytophilum inhibits human neutrophil apoptosis via upregulation of bfl-1, maintenance of mitochondrial membrane potential, and prevention of caspase 3 activation. Cell. Microbiol. 7: 29-38.  [Link to Pubmed]
49. Lin, Q., Y. Rikihisa. R. F. Massung, and Z. Woldehiwet. (2004) p44 polymorphism and transcription in a unique genomic locus in Anaplasma phagocytophilum strains from diverse geographic regions. Infect. Immun. 72: 5574-5581.  [Link to Pubmed]
50. Wang, X., Y. Rikihisa, T. Lai, Y. Kumagai, N. Zhi, and S. M. Reed. (2004) Rapid sequential changeover of expressed p44 genes during the acute phase of Anaplasma phagocytophilum infection in horses. Infect. Immun. 72: 6852-6859. [PMCID: PMC529143] | [Link to Pubmed]
51. Rikihisa, Y., C. Zhang, M. Kanter, Z. Cheng, N. Ohashi, and T. Fukuda. (2004) Analysis of p51 encoding a major antigen P51 in Neorickettsia species: obligatory intracellular bacteria of trematodes and mammals. J. Clin. Microbiol. 42: 3823-3826. [PMCID: PMC497601] | [Link to Pubmed]
52. Kawahara, M., Y. Rikihisa, E. Isogai, M. Takahashi, H. Misumi, C. Suto, S. Shibata, C. Zhang and M. Tsuji. (2004) Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae isolated from wild rats and found in Ixodes ovatus ticks. Int. J. Syst. Evol. Microbiol. 54: 1837-1843.  [Link to Pubmed]
53. Lin, Q., Y. Rikihisa, S. Felek, X. Wang, R. F. Massung, and Z. Woldehiwet. (2004) Anaplasma phagocytophilum has functional msp2 distinct from p44s. Infect. Immun. 72: 3883-3889.  [Link to Pubmed]
54. Wagner, E., W.G. Bremer, Y. Rikihisa, S.A. Ewing, G.R. Needham, A. Unver, X. Wang, R.W. Stich. (2004) Development of a p28-based PCR assay for Ehrlichia chaffeensis. Mol. Cell Probes. 18: 111-116.  [Link to Pubmed]
55. Rikihisa, Y. (2004) Rickettsial diseases. In: Equine Internal Medicine. 2nd Edition. Ed. by S.M. Reed, W. Bayly and D.C. Sellon eds. W.B. Saunders. 96-109.  [Link to Pubmed]
56. Zhang, C., Y. Rikihisa. (2004) Proposal to transfer 'Aegyptianella ranarum', an intracellular bacterium of frog red blood cells, to the family Flavobacteriaceae as 'Candidatus Hemobacterium ranarum' comb. nov. Environ. Microbiol. 6: 568-573.  [Link to Pubmed]
57. Felek, S., S.Telford IIIrd, R. C. Falco, and Y. Rikihisa (2004) Sequence analysis of p44 homologs expressed by Anaplasma phagocytophilum in infected ticks feeding on naïve hosts and in mice infected by tick attachment Infect. Immun. 72: 659-666.  [Link to Pubmed]
58. Lin, M., and Y. Rikihisa. (2004) Ehrlichia chaffeensis Downregulates Surface Toll-like Receptors 2/4, CD14, and Transcription Factors PU.1, and Inhibits LPS Activation of NF-kappaB, ERK 1/2, and p38 MAPK in Host Monocytes. Cell. Microbiol. 6: 175-186.  [Link to Pubmed]
59. Unver, A., Rikihisa, Y., Kawahara, M., and Yamamoto, S. (2003) Analysis of 16S rRNA gene sequences of Ehrlichia canis, Anaplasma platys, and Wolbachia species from canine blood in Japan. Ann. N. Y. Acad. Sci. 990: 692-698.  [Link to Pubmed]
60. Rikihisa, Y., C. Zhang, and B. M. Christensen. (2003) Molecular characterization of Aegyptianella pullorum (Rickettsiales, Anaplasmataceae) J. Clin. Microbiol. 41: 5294-5297.  [Link to Pubmed]
61. Felek, S, H. Huang, and Y. Rikihisa. (2003) Sequence and expression analysis of virB9 of the type IV secretion system of Ehrlichia canis strains in ticks, dogs, and cultured cells. Infect. Immun. 71: 6063-6067.  [Link to Pubmed]
62. Lin, Q., Y. Rikihisa, N. Ohashi, and N. Zhi. (2003) Mechanisms of Variable p44 Expression by Anaplasma phagocytophilum. Infect. Immun. 71: 5650-5661.  [Link to Pubmed]
63. Okada, H., H. Usuda, T. Tajima, M. Kawahara, T. Yoshino, and Y. Rikihisa. (2003) Detection and localization of Ehrlichia sp. HF strain most closely related to Ehrlichia chaffeensis in a mouse model by in situ hybridization. J. Comp. Pathol. 128: 182-187.  [Link to Pubmed]
64. Felek, S., R. Greene, and Y. Rikihisa. (2003) Transcriptional Analysis of p30 Major Outer Membrane Protein Genes of Ehrlichia canis in Naturally Infected Ticks and Sequence Analysis of p30-10 of E. canis from Diverse Geographic Regions. J. Clin. Microbiol. 41: 886-888.  [Link to Pubmed]
65. Lin, M., and Y. Rikihisa. (2003) Obligatory intracellular parasitism by Ehrlichia chaffeensis and Anaplasma phagocytophilum involves caveolae and glycosylphosphatidylinositol-anchored proteins. Cell. Microbiol. 5: 809-820.  [Link to Pubmed]
66. Lin, M., and Y. Rikihisa. (2003) Ehrlichia chaffeensis and Anaplasma phagocytophilum Lack Genes for Lipid A Biosynthesis and Incorporate Cholesterol for Their Survival. Infect. Immun. 71: 5324-5331. [PMCID: PMC187327] | [Link to Pubmed]
67. Harasawa, Y., M. Kawahara, and Y. Rikihisa. (2002) Characteristics of the 16S-23S rRNA intergenic spacer region of Mycoplasma haemomuris, previously classified as Haemobartonella muris. J. Vet. Med. Sci. 64: 1161-1164.  [Link to Pubmed]
68. Zhi, N., N. Ohashi, and Y. Rikihisa. (2002) Activation of a p44 pseudogene in Anaplasma phagocytophila by bacterial RNA splicing: A novel mechanism for posttranscriptional regulation of a multigene family encoding immunodominant major outer membrane proteins. Mol. Microbiol. 46: 135-146.  [Link to Pubmed]
69. Kim, H-Y. J. Mott, N. Zhi, T. Tajima, Y. Rikihisa. (2002) Cytokine Gene Expression by Peripheral Blood Leukocytes in Horses During Experimental Infection with Anaplasma phagocytophila. Clin. Diag. Lab. Immunol. 9: 1079-1084.  [Link to Pubmed]
70. Lin, Q. N. Zhi, N. Ohashi, H. W. Horowitz, M.E. Aguero-Rosenfeld, J. Ruffalli, G. P.Wormser, and Y. Rikihisa. (2002) p44 Gene Expression by Anaplasma phagocytophila in Acutely Infected Patients. J. Clin. Microbiol. 40: 2981-2988.  [Link to Pubmed]
71. Allison M. Liddell, John W. Sumner, Christopher D. Paddock, Y. Rikihisa, A. Unver, Richard S. Buller, and Gregory A. Storch. (2002) Reinfection with Ehrlichia chaffeensis in a Liver Transplant Recipient. Clin. Infect. Dis. 34: 1644-1647.  [Link to Pubmed]
72. Kim, Y-H, and Y. Rikihisa. (2002) Proinflammatory Cytokine mRNA Expression in Human Peripheral Blood Leukocytes in Response to Anaplasma phagocytophila through Activation of Nuclear Factor-kB and p38 Mitogen-Activated Protein Kinase. Infect. Immun. 70: 4132-4141.  [Link to Pubmed]
73. Unver, A., Y. Rikihisa, R.W. Stich, N. Ohashi, and S. Felek. (2002) The omp-1 Major Outer Membrane Multigene Family of Ehrlichia chaffeensis is Differentially Expressed in Canine and Tick Hosts. Infect. Immun. 70: 4701-4704.  [Link to Pubmed]
74. Zhang, C., and Y. Rikihisa. (2002) Evaluation of Sensitivity and Specificity of Mycoplasma haemomuris-Specific PCR. Comp. Med. 52: 204-206.  [Link to Pubmed]
75. Neimark, H., K-E Johansson, Y. Rikihisa, and J. Tilly. (2002) Revision of haemotrophic Mycoplasma species names. Int. J. Syst. Evol. Microbiol. 52: 683.  [Link to Pubmed]
76. Stich, R. W. Y.Rikihisa, S.A. Ewing, G.R. Needham, D. L. Grover and S. Jittapalapong. (2002) Detection of Ehrlichia canis in Canine Carrier Blood and in Individual Experimentally Infected Ticks with a p30-Based PCR Assay. J. Clin. Microbiol. 40: 540-546.  [Link to Pubmed]
77. Ohashi, N., N. Zhi, Q. Lin, and Y. Rikihisa. (2002) Characterization and Transcriptional Analysis of Gene Clusters for a Type IV Secretion Machinery in Human Granulocytic and Monocytic Ehrlichiosis Agents. Infect. Immun. 70: 2128-2138.  [Link to Pubmed]
78. Zhi, N., N. Ohashi, T. Tajima, J. Mott, R. W. Stich, D. Grover, S. R. Telford III, Q. Lin, and Y. Rikihisa. (2002) Transcript Heterogeneity of p44 Multigene Family in Human Granulocytic Ehrlichiosis Agent Transmitted by Ticks. Infect. Immun. 70: 1175-1184.  [Link to Pubmed]
79. Mott, J., Y. Rikihisa and S. Tsunawaki. (2002) Effects of Anaplasma phagocytophila on NADPH Oxidase Components in Human Neutrophils and HL-60 cells. Infect. Immun. 70: 1359-1366.  [Link to Pubmed]
80. Mott, J., Y. Muramatsu, E. Seaton, C. Martin, S. Reed, and Y. Rikihisa. (2002) Molecular Analysis of Ehrlichia risticii in Adult aquatic Insects in Pennsylvania, in Horses infected by ingestion of insects, and isolated in cell culture. J. Clin. Microbiol. 40: 690-693.  [Link to Pubmed]
81. Lin, M., Michael X. Zhu, and Y. Rikihisa. (2002) Rapid activation of PLC-gamma2, increase in cytosolic free calcium, recruitment of PLC-gamma2 and tyrosine phosphorylated proteins to its inclusion by Ehrlichia chaffeensis for internalization and growth in THP-1 cells. Infect. Immun. 70: 889-898. [PMCID: PMC127685] | [Link to Pubmed]
82. Dumler, J.S., A.F. Barbet, C.P.J. Bekker, G.A. Dasch, G.H. Palmer, S.C. Ray, Y. Rikihisa, and F. R. Rurangirwa. (2001) Reorganization of Genera in the Families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales; Unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia, and Ehrlichia with Neorickettsia; Description of six new species combinations; and Designation of Ehrlichia equi and "HGE agent" as subjective synonyms of Ehrlichia phagocytophila. Int. J. Syst. Evol. Microbiol. 51: 2145-2165.  [Link to Pubmed]
83. Unver, A., S. Felek, N. Zhi, C. Paddock, H. W. Horowitz, G. P.Wormser, and Y. Rikihisa. (2001) Western Immunoblot Analysis of HME and HGE dual reactive sera. J. Clin. Microbiol. 39: 3982-3986.  [Link to Pubmed]
84. Felek, S., A. Unver, R.W. Stich, and Y. Rikihisa. (2001) Sensitive detection of Ehrlichia chaffeensis in cultured cells, blood, and ticks by RT-PCR. J. Clin. Microbiol. 39: 460-463.  [Link to Pubmed]
85. Neimark, H., K-E Johansson, Y. Rikihisa, and J. Tilly. (2001) Proposal to transfer some members of the genera Haemobartonella and Eperythrozoon to the Genus Mycoplasma with descriptions of 'Candidatus Mycoplasma hemofelis', 'Candidatus Mycoplasma hemomuris', 'Candidatus Mycoplasma hemosuis' and 'Candidatus Mycoplasma wenyonii'. Int. J. Syst. Evol. Microbiol. 51: 891-899.  [Link to Pubmed]
86. Unver, A., M. Perez, N..Orellana, H. Huang, and Y. Rikihisa. (2001) Molecular and antigenic comparison of Ehrlichia canis from dogs, ticks, and a human in Venezuela. J. Clin. Microbiol. 39: 2788-2793.  [Link to Pubmed]
87. Unver, A., N. Ohashi, T. Tajima, R.W. Stich, D. Grover, and Y. Rikihisa. (2001) Transcriptional analysis of p30 major outer membrane multigene family of Ehrlichia canis in dogs, ticks, and cell culture at different temperatures. Infect. Immun. 69: 6172-6178.  [Link to Pubmed]
88. Ohashi, N., Y. Rikihisa, and A. Unver. (2001) Analysis of transcriptionally active gene clusters of major outer membrane protein multigene family in Ehrlichia canis and E. chaffeensis. Infect. Immun. 69: 2083-2091.  [Link to Pubmed]
89. Okada, H., T. Tajima, M. Kawahara, and Y. Rikihisa. (2001) Ehrlichial proliferation in endothelial cells and lethal liver necrosis in immunocompetent mice experimentally infected with HF strain most closely related to Ehrlichia chaffeensis. J. Comp. Pathol. 124: 165-171.  [Link to Pubmed]
90. Yoshiie, K., Kim, H.Y., Mott, J., and Y. Rikihisa. (2000) Intracellular infection by human granulocytic ehrlichiosis agent inhibits human neutrophil apoptosis. Infect. Immun. 68: 1125-1133.  [Link to Pubmed]
91. Shibata, S., M. Kawahara, Y. Rikihisa, H. Fujita, Y. Watanabe, C. Suto, and T. Ito. (2000) New Ehrlichia sp. closely related with E. chaffeensis isolated from Ixodes ovatus ticks in Japan. J. Clin. Microbiol. 38: 1331-1338.  [Link to Pubmed]
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139. Iqbal, Z. and Y. Rikihisa. (1994) Application of polymerase chain reaction for detection of Ehrlichia canis in tissues of dogs. Vet. Microbiol. 42: 281-287.  [Link to Pubmed]
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